Lauren Tom's first role in television was that of Miko Wakamatsu on The Facts of Life. She subsequently appeared on The Equalizer, Catfish With Black Bean Sauce, thirtysomething, Quantum Leap, Chicago Hope, Homicide: Life on the Street, Grace Under Fire, Friends, The Nanny, The Middle, DAG, The Division, Monk, My Wife and Kids, Barbershop: The Series, Grey's Anatomy, The Closer and Men in Trees. She had an acting role in a bonus feature on the Futurama: Into the Wild Green Yonder DVD. She also had a supporting role on the 8th and 9th season of the drama series Supernatural as prophet Kevin Tran's mother, Linda Tran. in 2018, she appeared in the second season of the Amazon Prime drama series Goliath.